中药抗病毒作用机制研究进展

Progress on Traditional Chinese Medicine in Anti-viral Mechanism

病毒是一类严重危害人畜健康的病原体,当前防控病毒性疾病仍以疫苗免疫为主,但由于病毒种类多样,变异频发,单纯的免疫已经无法起到有效的防控作用。因此,开发理想的抗病毒药物已成为近年来国内外学者关注的重点问题。目前临床应用的抗病毒药物品种较少,效果不理想,且副作用大,由此中药因其独特的疾病防治优势,走进了众多学者的视线。研究显示,多种中药饮片、复方及其有效成分均对病毒有较强的抑制作用。论文结合病毒性疾病的发病机理,对中药抗病毒作用机制的研究成果进行综述,以期为兽医临床研发高效低毒的抗病毒药物提供参考。

Virus seriously endangers the health of human and animal.Currently,the prevention and control of viral diseases still mainly rely on the vaccine immunization.However,due to the variety of viruses and frequent mutations,immunization alone has been unable to play an effective role in prevention and control.Therefore,the development of ideal anti-viral drugs has become the focus of scholars at home and abroad in recent years.At present,there are few varieties of anti-viral drugs in clinical application,with unsatisfactory effects and great side effects.Therefore,traditional Chinese medicine(TMC)has attracted the attention of many scholars due to its unique advantages in disease prevention and treatment.The study showed that a variety of TCM decoction pieces,compound preparations and their active components all had strong inhibitory effect on virus.In this paper,combined with the pathogenesis of viral diseases,the research results of anti-viral mechanism of TMC were reviewed,in order to lay a theoretical foundation for the research and development of high efficiency and low toxicity antiviral drugs in veterinary clinic.