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关节炎中滑膜增生的研究进展

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摘要 滑膜增生是类风湿性关节炎的主要特征,也是其他关节炎如血友病性关节炎和骨关节炎中不可忽视的病理改变之一。本文通过对中国知网、万方数据库、PubMed和Web of Science等数据库的相关检索结果进行归纳分析,总结了滑膜增生的主要细胞来源、滑膜异常增生对关节的影响和参与调控滑膜增生的诸多信号通路。最后,我们强调了成纤维样滑膜细胞的增殖、凋亡、自噬和铁死亡等细胞死亡机制在滑膜增生中的重要作用,期望对于整体阐明滑膜病变在关节疾病进程中的作用有所帮助。
出处 《骨科》 CAS 2023年第6期580-584,共5页 ORTHOPAEDICS
基金 国家自然科学基金(82172498)。
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