肌因子在抗阻训练诱导的骨骼肌肥大中的作用及研究进展

The role and research progress of myokines in skeletal muscle hypertrophy induced by resistance training

骨骼肌在运动过程中分泌的肽类和细胞因子,即肌因子,对于促进骨骼肌肥大、提高骨骼肌力量均具有重要调节作用。研究表明抗阻训练诱导骨骼肌释放的肌因子能促进骨骼肌肥大。本文首先介绍了肌因子的发现和功能以及抗阻训练诱导骨骼肌肥大的机制,然后综述了胰岛素样生长因子-1、鸢尾素、白细胞介素-6、白细胞介素-15、肌肉生长抑素、核心蛋白聚糖和卵泡抑素几种公认的肌因子在抗阻训练诱导的骨骼肌肥大中的作用和研究进展。

The peptides and cytokines secreted by skeletal muscles during training,namely myokines,play an important regulatory role inpromoting skeletal muscle hypertrophy and in improving skeletal muscle strength.The myokines induced by resistance training could produce skeletal muscle hypertrophy.This review firstly introduced the discovery and function of myokines as well as the mechanism of skeletal muscle hypertrophy induced by resistance training.Then reviewed the role and research progress of several recognized myokines in resistance training-induced skeletal muscle hypertrophy,including insulin-like growth factor-1,irisin,interleukin-6,interleukin-15,myostatin,decorin,and follistatin.