市售鸡肉与鸡蛋中四环素类抗生素残留调查与膳食暴露风险评估

Investigation and dietary exposure risk assessment of tetracycline antibiotics residues in eggs and chicken sold on the market

目的了解杭州地区市售鸡肉与鸡蛋中四环素类抗生素残留的污染状况,探讨其污染来源,评价其膳食安全性。方法2021年在杭州市随机抽取66份鸡肉样品和71份鸡蛋样品,采用液相色谱-质谱/质谱法监测四环素类抗生素(四环素、土霉素、金霉素和强力霉素),采用食品安全指数来评估样品中四环素类抗生素的残留风险。结果鸡肉中检出强力霉素与土霉素,检出率分别为45.4%和1.52%,四环素与金霉素均未检出,无超标样品;鸡蛋中强力霉素检出率与超标率均为1.41%,其余项目均未检出;鸡肉与鸡蛋中四种四环素的食品安全指数远<1,说明其污染程度对食品安全影响很小。结论杭州地区市售鸡肉和鸡蛋中存在一定的四环素类抗生素残留,但污染程度较轻,鸡肉与鸡蛋的安全状态均为可接受。

Objective To determine the levels of tetracycline antibiotic residues in eggs and chicken sold on the market in Hangzhou,the pollution sources were explored,and their dietary exposure risk was evaluated.Methods A total of 66 chicken and 71 egg samples were randomly collected from Hangzhou in 2021 for the detection of tetracycline antibiotics by ultra performance liquid chromatography-tandem mass spectrometry,including tetracycline,oxytetracycline,aureomycin,and doxycycline.The risk of tetracycline antibiotic residues in samples was evaluated by food safety index.Results The detection rate of doxycycline and oxytetracycline in chicken samples were 45.4%and 1.52%,respectively.Tetracycline and aureomycin residues were not detected,and no samples exceeded the standards.Of the four antibiotics,only doxycycline residues were detected in egg samples,and the detection rate and over standard rate were both 1.41%.The overall food safety indices of four tetracyclines were less than one,indicating that eggs and chicken in Hangzhou were safe for consumption.Conclusion Tetracycline antibiotics residues were found in eggs and chicken in Hangzhou,while the overall contamination level was low.The safety status of eggs and chicken in Hangzhou was thus considered acceptable.