主动脉内球囊反搏患者拔除后使用Angio-Seal血管闭合装置与人工压迫的止血效果及并发症的比较

Comparison of Hemostatic Effect and Complications Between Angio-Seal Vascular Closure Device and Manual Compression in Patients After Removing Intra-Aortic Balloon Pump

目的对比Angio-Seal血管闭合装置与人工压迫在主动脉内球囊反搏(IABP)拔除后的止血效果及并发症的发生率。方法纳入220例行IABP留置超过12 h的患者,根据拔除IABP后是否使用Angio-Seal血管闭合装置将所有患者分为Angio-Seal组和人工压迫组。观察拔出IABP后出血、血肿、假性动脉瘤、腹膜后血肿、血管迷走神经反射及腰背部不适发生率。结果两组出血、血肿、假性动脉瘤、腹膜后血肿等并发症发生率无显著差异(P>0.05),但Angio-Seal组血管迷走神经反射和腰背部不适发生率更低(P<0.05)。结论在留置时间超过12 h的IABP患者中,使用Angio-Seal血管闭合装置和人工压迫相比并未增加患者的出血和相关并发症的风险,同时可改善患者不适程度。

Objective To compare the hemostatic effect and incidence of complication of Angio-Seal vascular closure device and manual compression after intra-aortic balloon pump(IABP)extraction.Methods A total of 220 patients with IABP over 12 h were randomised into the Angio-Seal group and the manual compression group based on whether using Angio-Seal closure device after removing IABP.The outcome events included the occurrence rates of bleeding,hematoma,pseudoaneurysm,retroperitoneal hematoma,vasovagal nerve reflex and lumbodorsal discomfort were observed after removing IABP.Results There was no significant difference between the two groups in the rates of bleeding and complications such as hematoma,pseudoaneurysm and retroperitoneal hematoma(P>0.05),while there existed a lower rate of vasovagal reflex and lumbodorsal discomfort in Angio-Seal group(P<0.05).Conclusion For patients with IABP over 12 h,the Angio-Seal vascular closure device did not increase the risk of bleeding and related complications compared to manual compression,while also improving patient discomfort.