药师干预对高血压患者合理用药的价值分析

Analysis of the Value of Pharmacist Intervention in Rational Medication Use in Patients with Hypertension

目的探讨对高血压患者给予药师干预后获得的临床效果。方法选取2020年2月—2022年4月宿迁市第一人民医院收治的160例高血压疾病患者作为研究对象,以投掷硬币法分组,其中施以常规用药干预的设为参照组(n=80),施以药师干预的设为研究组(n=80)。对比两组患者不合理用药(遴选药品不适宜、重复给药、联合用药不合理、剂量不合理)总发生率、血压测定结果(舒张压水平以及收缩压水平)。结果研究组不合理用药(遴选药品不适宜、重复给药、联合用药不合理、剂量不合理)总发生率低于参照组,差异有统计学意义(P<0.05)。干预前,两组舒张压、收缩压比较,差异无统计学意义(P>0.05);干预后,研究组舒张压(75.29±2.29)mmHg以及收缩压(117.49±4.61)mmHg均低于参照组(92.28±2.55)、(122.25±4.45)mmHg,差异有统计学意义(t=44.339、6.645,P<0.05)。结论临床对高血压患者合理给予药师干预,可将患者遴选药品不适宜、重复给药、联合用药不合理、剂量不合理等发生率显著降低,将舒张压水平以及收缩压水平显著降低,获得理想疾病干预效果。

Objective To explore the clinical effects of pharmacist intervention on patients with hypertension.Meth-ods A total of 160 patients with hypertension treated in the First People's Hospital of Suqian City from February 2020 to April 2022 were selected as the study objects and divided into groups by coin tossing method.The patients receiv-ing conventional medication intervention were set as the reference group(n=80),and the patients receiving pharma-cist intervention were set as the study group(n=80).The total incidence of irrational drug use(inappropriate selec-tion of drugs,repeated administration,unreasonable combination of drugs,unreasonable dose)and blood pressure measurement results(diastolic and systolic blood pressure levels)were compared between the two groups.Results The total incidence of irrational drug use(inappropriate selection of drugs,repeated administration,irrational combi-nation of drugs,and irrational dosage)in the study group was lower than that in the reference group,and the differ-ence was statistically significant(P<0.05).Before intervention,there was no statistically significant difference in dia-stolic and systolic blood pressure between the two groups(P>0.05).After intervention,the diastolic blood pressure(75.29±2.29)mmHg and systolic blood pressure(117.49±4.61)mmHg in the study group were lower than those in the control group(92.28±2.55)mmHg and(122.25±4.45)mmHg,and the differences were statistically significant(t=44.339,6.645,P<0.05).Conclusion Reasonable intervention by pharmacists in clinical practice can significantly re-duce the incidence of inappropriate drug selection,repeated administration,unreasonable combination therapy,and unreasonable dosage for patients with hypertension,and significantly reduce the levels of diastolic and systolic blood pressure,achieving ideal disease intervention effects.