等张液体在重症肺炎患儿中的治疗效果及对低钠血症发生情况、血气分析指标的影响

Treatment Effect of Isotonic Solution in the Children with Severe Pneumonia and Influence for Hyponatremia Occurrence and Blood Gas Analysis Indexes

目的:探究等张液体在重症肺炎患儿中的治疗效果及对低钠血症发生情况、血气分析指标的影响。方法:将2021年9月—2023年3月宁德师范学院附属宁德市医院的104例重症肺炎患儿根据随机数表法分为对照组52例和观察组52例。对照组采用低张液体进行干预,观察组则采用等张液体进行干预。比较两组治疗总有效率、治疗前后血气分析指标[动脉血二氧化碳分压(PaCO_(2))及动脉血氧分压(PaO_(2))]、血钠水平、低钠血症发生率及住院天数。结果:观察组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。治疗1 d、2 d及3 d,观察组PaCO_(2)显著低于对照组,PaO_(2)显著高于对照组,差异有统计学意义(P<0.05)。治疗1 d、2 d及3 d,观察组血钠水平则显著高于对照组,差异有统计学意义(P<0.05)。观察组低钠血症发生率显著低于对照组,差异有统计学意义(P<0.05)。观察组住院天数显著短于对照组,差异有统计学意义(P<0.001)。结论:等张液体在重症肺炎患儿中的治疗效果较好,有助于降低低钠血症的发生率及改善血气分析指标,缩短住院天数。

Objective:To investigate the treatment effect of isotonic solution in the children with severe pneumonia and influence for hyponatremia occurrence and blood gas analysis indexes.Method:A total of 104 children with severe pneumonia from September 2021 to March 2023 in Ningde City Hospital Affiliated to Ningde Normal University were selected and they were divided into control group 52 cases and observation group 52 cases according to the random number table.The control group was treated with hypotonic solution,the observation group was treated with isotonic solution.Then the total effective rate,blood gas analysis indexes[partial pressure of arterial carbon dioxide(PaCO2),partial pressure of arterial oxygen(PaO2)],blood sodium levels before and after treatment,hyponatremia rate and hospitalization time of the two groups were compared.Result:The total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).At 1 d,2 d and 3 d of treatment,PaCO2 in the observation group was significantly lower,and PaO2 was higher than that in the control group,and the differences were statistically significant(P<0.05).The serum sodium levels of the observation group were significantly higher than that of the control group after 1 d,2 d and 3 d of treatment,and the differences were statistically significant(P<0.05).The incidence of hyponatremia in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).The hospitalization time in the observation group was significantly shorter than that in the control group,the difference was statistically significant(P<0.001).Conclusion:The application effect of isotonic solution in the children with severe pneumonia is better than hypotonic solution,and it helps to improve blood gas analysis and reduce the occurrence of hyponatremia,shorten the hospitalization time.