亚麻籽木酚素的提取及其生物活性研究进展

Research Progress on the Extraction and Bioactivity of Flaxseed Lignan

木酚素作为亚麻籽中主要的活性成分之一,因其具有抗癌、抗氧化、抗炎、预防糖尿病和保护心血管等功效,近年来备受关注。为深入了解亚麻籽木酚素的开发利用情况,在国内外文献综述的基础上,主要从亚麻籽木酚素的提取工艺和生物活性的应用进行了概述。亚麻籽木酚素的有效提取是研究生物活性的基础,不同的提取工艺不仅会造成木酚素提取率上的差异,还会影响其生物活性。因此概括了亚麻籽木酚素常用的提取方法,包括有机溶剂法、亚临界水提法、微生物发酵法等,同时总结了亚麻籽木酚素的生物活性,并着重归纳了木酚素在医药领域的研究进展。最后对亚麻籽木酚素今后的研究提出了展望,旨在为亚麻籽木酚素在医药产业和大健康产业等领域的深入研究及开发应用提供理论依据。

Lignan is considered one of the most important bio-active components in flaxseed,and has attracted attention in recent years because of the efficacies of anti-cancer,antioxidation,anti-inflammation,diabetes prevention and cardiovascular system protection.In order to make a better understanding of the exploitation and utilization of flaxseed lignan,based on the domestic and foreign literature reviews,this article mainly reviewed the research progress on the extraction technology and biological activity application of flaxseed lignan.The effective extraction of lignan from flaxseed is the basis of bioactivity research.Different extraction processes can not only cause the difference in the extraction rate of lignan,but also affect its biological activity.This article summarizes some commonly used extraction methods for flaxseed lignan,including organic solvent extraction,subcritical water extraction and microbial fermentation.At the same time,the application of bioactivities is summed up and the research progress of lignan in the pharmaceutical field is emphasized.This article proposes prospects for the future research direction of flaxseed lignan,aiming to provide theoretical basis for the in-depth research,development and application of flaxseed lignan in the fields of medical industry and health industry.