纳米酶在生物医药领域应用的研究进展

Recent Research Progress in Nanozyme and Their Biomedical Applications

纳米酶是一类既有纳米材料的独特性能,又有催化功能的模拟酶。近年来,由于交叉学科的爆炸式发展,关于纳米酶的研究呈指数性增长。为了突出纳米酶在生物医药领域的研究成果,帮助相关研究人员了解纳米酶在该领域的研究现状,本文概述了纳米酶在生物医药领域的应用研究新进展。从纳米酶在疾病治疗和疾病诊疗一体化研究两个方面出发,总结了纳米酶在生物医药领域的研究进展。在疾病治疗领域,纳米酶用于肿瘤、炎症、细菌感染和心脑血管相关疾病治疗的应用研究。总结了纳米酶联合光声成像、磁共振成像与和光热成像技术等在疾病诊疗一体化领域的研究新进展。对纳米酶未来的研究方向和发展趋势进行了展望。

Nanozymes are mimetic enzymes that have both the properties of nanomaterials and catalytic activities.In recent years,research on nanozymes has grown exponentially due to the explosive development of cross⁃disciplinary.To highlight the research results of nanozymes in biomedicine,and to help relevant researchers understand the status of nanozymes research,this review outlines the recent progress in research on applications of nanozymes in biomedicine from two aspects:nanozymes in disease treatment and integrat⁃ed research in disease theranostics.Firstly,in the field of disease treatment,it is been summarized the applications of nanozymes for the treatment of tumors,inflammation,bacterial infection,and cardiovascular⁃related diseases.After that,it is been summarized the state⁃of⁃art⁃in nanozymes combined with photoacoustic imaging,magnetic resonance imaging,and photothermal imaging technologies in disease diagnosis and treatment.Finally,future research directions and development trends of nanozymes are prospected.