张家口地区≥40岁人群膝关节骨性关节炎患病影响因素研究

Influencing factors of knee osteoarthritis in people≥40 years old in Zhangjiakou area

目的 分析张家口地区≥40岁居民膝关节骨性关节炎(KOA)患病现状并探讨其患病影响因素。方法选择张家口地区≥40岁居民进行问卷调查,予膝关节正侧位X射线检查,调查KOA患病现状,再用多因素logistic回归分析KOA患病危险因素。结果 纳入分析的1 264名张家口≥40岁居民中KOA最终诊断279例,患病率为22.07%。多因素logistic回归分析结果显示女性(OR=2.248)、超重/肥胖(OR=1.389)、有KOA家族史(OR=2.125)、有膝关节手术史(OR=2.543)、合并糖尿病(OR=3.426)、(曾)居住环境潮湿/阴暗(OR=3.986)、常爬楼梯(OR=4.537)均是张家口地区≥40岁人群KOA患病的独立危险因素,常吃海产品(OR=0.422)是保护因素。结论张家口地区≥40岁居民KOA患病率较高,女性、超重/肥胖、有KOA家族史、有膝关节手术史、合并糖尿病、(曾)居住环境潮湿/阴暗、常爬楼梯的居民应作为KOA发生的高风险人群开展预防工作,建议保证海产品的食用习惯。

Objective To analyze the prevalence and influencing factors of knee osteoarthritis(KOA)in resi-dents≥40 years old in Zhangjiakou area.Methods The residents≥40 years old in Zhangjiakou area were selected for questionnaire survey,their knee joints were examined with anteroposterior and lateral X-ray.The prevalence of KOA was investigated,and the risk factors of KOA were analyzed with multivariate logistic regression.Results Among the 1264 residents≥40 years old in Zhangjiakou,279 cases were finally diagnosed with K0A,and the prevalence rate was 22.07%.Multivariate logistic regression analysis showed that women(OR=2.248),overweight/obesity(OR=1.389),family histo-ry of KOA(OR=2.125),history of knee surgery(OR=2.543),combined diabetes(OR=3.426),damp/dark living envi-ronment(OR=3.986),and frequent stair climbing(OR=4.537)were independent risk factors for KOA in people≥40 years old in Zhangjiakou area,and frequent eating seafood(OR=0.422)was a protective factor.Conclusions In Zhangjiakou,the prevalence rate of KOA is higher in residents≥40 years old.Women,overweight/obese,family history of KOA,history of knee surgery,combined diabetes,damp/dark living environment,and frequent stair climbing residents should be considered as the high-risk group for KOA prevention.It is recommended to ensure the consumption habit of sea-food.