胰腺癌中医治疗评述

Review on Traditional Chinese Medicine Treatment of Pancreatic Cancer

对胰腺癌相关的经典及现代研究进行分析,认识到胰腺癌病位在脾,与肝相关,病机概括为本虚标实、虚实夹杂,以脾虚为本,又兼气滞,内生湿、热、痰、瘀血,复受癌毒侵犯为标。基于病因病机认识的基础上,认为胰腺癌的基本治则应以补虚健脾为本,酌情辅以理气、祛湿、清热、化痰、散瘀、外祛癌毒,同时不忘与调肝并行。并就现代中药方剂应用、中药注射剂、穴位敷贴、针刺、电针、经皮神经电刺激、耳穴压丸、灸法方面对于胰腺癌的现代中医治疗进行总结,认识到现代中医治疗中,方药、穴位选取原则多以健脾兼疏肝为要,与基本治则相符。进一步研究发现,现代中医治疗能抑制胰腺癌细胞生长,延长患者生存期,降低患者肿瘤指标,缓解患者放化疗不良反应,改善患者癌痛、呃逆、恶心、呕吐、术后胃瘫、抑郁、失眠等一般状况。

By analyzing the classical and modern studies related to pancreatic cancer,we realize that the pancreatic cancer is located in the spleen,which is related to the liver.The pathogenesis is summarized as deficiency of the original.The specific interpretation is based on spleen deficiency,coupled with Qi stagnation,endogenous dampness-heat phlegm and blood stasis,and repeatedly invasion by cancer poison.Based on the understanding of etiology and pathogenesis,the basic treatment of pancreatic cancer should be based on supplementing the deficiency and strengthening the spleen,regulating Qi,dampness removal,heat clear,phlegm dissolve,stasis disperse,and external cancer toxin,while not forgetting to regulate the liver.We also summarize the modern TCM treatment of pancreatic cancer in terms of modern Chinese medicine formulas,Chinese medicine injections,acupoint dressing,acupuncture,electroacupuncture,percutaneous nerve stimulation,ear pressure pills,and moxibustion,and realize that in modern Chinese medicine treatment,the principles of prescription medicine and acupoint selection are mostly based on strengthening the spleen and regulate the liver,which is consistent with the basic treatment principles.Further studies have found that modern traditional Chinese medicine treatment can inhibit the growth of pancreatic cancer cells,prolong the survival of patients,reduce tumor indicators,alleviate the adverse reactions of radiotherapy and chemotherapy,and improve the general conditions of patients such as cancer pain,hiccups,nausea and vomiting,postoperative gastric paralysis,depression,insomnia.