纺织基微流体的修饰与改性

Fabrication and Modification of Textile-based Microfluidics

微流体对生化反应起着重要的作用,纺织基微流体因其结构可调,为微流体生化反应提供了新的工具。然而传统的纺织基微流体,因其亲水性有限并且非特异性吸附严重,限制了其在生化领域中的应用。通过在纺织纤维上修饰硝酸纤维素,利用硝酸纤维素对蛋白和核酸的特异性结合能力,以及对非特异性吸附的降低,改善其在生化领域中的应用。并且将等离子体处理和多层硝酸纤维素修饰相结合,调控纺织基微流体的流体特性,为纺织基微流体材料在生化领域中的应用提供新的途径。

Microfluidic flow plays an important role in biochemical reaction.Textile-based microfluidics provide a new tool for microfluidic biochemical reaction due to its adjustable structure.However,traditional textilebased microfluidics have limited hydrophilicity and severe non-specific adsorption,which limits their application in the field of biochemistry.The textile fiber was modified with multilayer nitrocellulose,enhancing proteins and nucleic acids binding ability and reducing nonspecific adsorption to expand its application in biochemical field.Combining with plasma treatment and multilayer cellulose nitrate modification,the fluid characteristics of textile-based microfluidics could be regulated,which provides a new way for the application of textilebased materials in biochemical field.