扬州市居民艾滋病非职业暴露后预防知晓情况调查

Awareness of HIV non-occupational post-exposure prophylaxis among residents in Yangzhou City

目的了解江苏省扬州市居民对艾滋病非职业暴露后预防(nPEP)的知晓情况,为大众人群的nPEP宣传和干预提供依据。方法于2022年1—6月,采用多阶段随机抽样方法抽取扬州市≥18岁常住居民开展问卷调查,收集人口学信息,nPEP知识知晓情况和艾滋病防治相关知识、态度及行为;采用多因素logistic回归模型分析nPEP知晓的影响因素。结果发放问卷1488份,有效问卷1447份,问卷有效率为97.24%。调查男性644人,女性803人;年龄为(36.33±11.90)岁;职业为机关企事业单位585人,占40.43%。了解艾滋病750人,占51.83%。艾滋病歧视程度低413人,占28.54%;中651人,占44.99%;高383人,占26.47%。有HIV抗体检测经历201人,占13.89%;定期健康体检792人,占54.73%。知晓nPEP 693人,知晓率为47.89%。多因素logistic回归分析结果显示,职业(机关企事业单位,OR=1.530,95%CI:1.170~1.999;学生,OR=1.450,95%CI:1.027~2.047)、了解艾滋病(OR=3.201,95%CI:2.495~4.106)、HIV抗体检测经历(OR=1.908,95%CI:1.339~2.719)、定期健康体检(OR=2.308,95%CI:1.807~2.949)和艾滋病歧视程度(中,OR=0.703,95%CI:0.532~0.928;高,OR=0.699,95%CI:0.502~0.974)是nPEP知晓的影响因素。结论扬州市居民nPEP知晓率有待提升,机关企事业单位人员和学生知晓水平相对较高。

Objective To investigate the awareness of HIV non-occupational post-exposure prophylaxis(nPEP)among residents in Yangzhou City,Jiangsu Province,so as to provide basis for further publicity and application of nPEP in genenral population.Methods Community residents at ages of 18 years and older in Yangzhou City were sampled us-ing the multi-stage random sampling method from January to June,2022,and a cross-sectional survey was conducted to collect their demographic information,acquired immune deficiency syndrome(AIDS)-related knowledge,attitude and behaviors and awareness of nPEP.A multivariable logistic regression model was used to identify factors affecting awareness of nPEP.Results Totally 1488 questionnaires were allocated,and 1447 valid questionnaires were recov-ered,with an effective recovery rate of 97.24%.There were 644 males and 803 females,with mean age of(36.33±11.90)years.There were 585 residents(40.43%)employed by government agencies,enterprises and public institutions;750 residents(51.83%)with awareness of AIDS;413(28.54%),651(44.99%)and 383 residents(26.47%)had low,me-dium and high levels of AIDS discrimination,respectively;201 residents(13.89%)with HIV detection experience;and 792 residents(54.73%)with regular health checkup.The awareness rate of nPEP was 47.89%.Multivariable logistic re-gression analysis identified career(government agencies,enterprises and public institutions,OR=1.530,95%CI:1.170-1.999;students,OR=1.450,95%CI:1.027-2.047),awareness of AIDS(OR=3.201,95%CI:2.495-4.106),having HIV de-tection experience(OR=1.908,95%CI:1.339-2.719),regular health checkup(OR=2.308,95%CI:1.807-2.949)and discrim-ination against AIDS(medium,OR=0.703,95%CI:0.532-0.928;high,OR=0.699,95%CI:0.502-0.974)as factors affect-ing awareness of nPEP.Conclusions The awareness of nPEP among residents in Yangzhou City needs to be improved.Employees in government agencies,enterprises and public institutions and students have higher awareness of nPEP.