Association between clinical phenotypes of hypertrophic cardiomyopathy and Ca^(2+)gene variation

Objective To observe the association between clinical phenotypes of hypertrophic cardiomyopathy(HCM)patients and a rare calcium channel and regulatory gene variation(Ca^(2+)gene variation)and to compare clinical phenotypes of HCM patients with Ca^(2+)gene variation,a single sarcomere gene variation and without gene variation and to explore the influence of rare Ca^(2+)gene variation on the clinical phenotypes of HCM.