动脉粥样硬化抗炎治疗的研究进展

RESEARCH ADVANCES IN ANTI-INFLAMMATORY THERAPY FOR ATHEROSCLEROSIS

动脉粥样硬化(AS)是一种慢性炎症性疾病。越来越多的研究表明,炎症贯穿于AS发生、发展的全过程,固有免疫和适应性免疫在AS的发生发展中均起着重要作用。炎症过程可能会成为预测和防治AS及其并发症的潜在靶点。本文对AS抗炎治疗的最新研究进展进行文献综述,以期为AS性心血管疾病的防治提供新的思路。

Atherosclerosis(AS)is a chronic inflammatory disease.A growing body of evidence has shown that inflammation is involved in the whole process of the development and progression of AS,in which innate immunity and adaptive immunity both play an important role.The inflammatory process may be a potential target for the prediction,prevention,and treatment of AS and its complications.This paper reviews latest research advances in the anti-inflammatory therapy of AS,aiming to provide new ideas for the prevention and therapy of AS-related cardiovascular disease.