左氧氟沙星滴耳液+地塞米松治疗急性化脓性中耳炎的疗效观察

Curative effect observation of levofloxacin ear drops and dexamethasone in the treatment of acute suppurative otitis media

目的观察研究左氧氟沙星滴耳液+地塞米松治疗急性化脓性中耳炎的疗效。方法此次临床研究以60名患有急性化脓性中耳炎的患者作为样本对象,所有对象均为我院收治且治疗时间集中在2021年6月至2022年6月期间内;将上述样本按照随机数字表法进行分组,一组命名为常规治疗组,另一组命名为联合治疗组,每组各30人;统计两组患者的治疗有效率、用药后的不良反应发生率及治疗前后的炎性因子水平。结果两组患者用药前的炎性因子水平无明显差异性,P>0.05;用药后,该组患者的IL-6、TNF-α、hs-CRP水平均出现显著降低;此外,相较于常规治疗组,联合治疗组患者的治疗有效率明显更高,其用药后的不良反应发生率更低,以上结果对比均具有统计学差异性,P<0.05。结论采取左氧氟沙星滴耳液+地塞米松的方案对急性化脓性中耳炎患者进行治疗能够有效提高患者的治疗有效率,且不良反应更少,安全性更高。相较于单纯用药治疗而言,其炎性因子水平得到显著下降,效果更加显著。

Objective To observe and study the efficacy of levofloxacin ear drops+dexamethasone in the treatment of acute suppurative otitis media.Methods This clinical study took 60 patients with acute suppurative otitis media as sample objects,all of whom were admitted to our hospital and the treatment time was concentrated in the period from June 2021 to June 2022;the above samples were randomized according to the The number table method was used for grouping,and one group was named the conventional treatment group,and the other group was named the combined treatment group,with 30 people in each group;the treatment efficacy rate,the incidence of adverse reactions after medication,and the inflammation before and after treatment were counted in the two groups.Sex factor levels.Results There was no significant difference in the levels of inflammatory factors between the two groups of patients before treatment,P>0.05;after treatment,the levels of IL-6,TNF-α,and hs-CRP in this group of patients were significantly reduced;In the conventional treatment group and the combined treatment group,the treatment efficiency was significantly higher,and the incidence of adverse reactions after treatment was lower.The comparison of the above results was statistically significant,P<0.05.Conclusion The regimen of levofloxacin ear drops+dexamethasone in the treatment of patients with acute suppurative otitis media can effectively improve the treatment efficiency of patients,with fewer adverse reactions and higher safety.Compared with drug treatment alone,the level of inflammatory factors was significantly reduced,and the effect was more significant.