中西医结合治疗急性淋巴细胞白血病合并新型冠状病毒感染(重型)恢复期患者1例

Integrated Traditional Chinese and Western Medicine Treatment for Acute Lymphoblastic Leukemia Complicated with Severe COVID-19 in Recovery Stage:A Case Report

报道1例急性淋巴细胞白血病合并新型冠状病毒感染(重型)恢复期的中西医结合治疗病案,以期为相关疾病的临床诊疗提供思路。患者急性淋巴细胞白血病化疗后骨髓抑制期感染新型冠状病毒,西医以抗感染及对症、支持治疗为主,进入恢复期后考虑化疗后病史及病势转归情况,整体辨证为气阴两虚、痰瘀互结证,基于“态靶结合”的辨治策略选方用药,厘清“虚态”“病靶”“症靶”,在西医治疗基础上予生脉散合复方浙贝颗粒组方加减以益气养阴扶正、养血凉血,最终获得满意疗效。

This paper reported a case of severe COVID-19 in the recovery stage with acute lymphoblastic leukemia treated by integrated traditional Chinese and western medicine,with the intention of shedding light on the clinical diagnosis and treatment of similar conditions.The patient,who had acute lymphoblastic leukemia,developed COVID-19infection during the bone marrow suppression period after chemotherapy.Treatment with western medicine was mainly anti-infection,symptomatic management,and supportive care.During the recovery stage,considering the patient's chemotherapy history and disease progression,the overall syndrome was identified as deficiency of both qi and yin and binding of phlegm and blood.Based on the“state-target”combined treatment strategy,herbal prescriptions were selected and modified to address the“deficiency state”,“disease target”,and“symptom target”.In addition to western medicine,the patient was administered with Shengmai Powder(生脉散)and Compound Zhebei Granules(复方浙贝颗粒)in its modifications to boost qi,nourish yin,and reinforce healthy qi,nourish and cool the blood,ultimately achieving satisfactory therapeutic effects.