薰衣草精油双重缓释纳米纤维的构建及其性能分析

Construction and properties analysis of lavender essential oil dualsustained-release nanofibers

针对生物、医药领域芳香疗法产品薰衣草精油高挥发、难以持久的问题,以薰衣草精油为芯材,β-环糊精为壁材,通过饱和水溶液法,利用分子间络合作用制备β-环糊精/薰衣草精油微胶囊,并使用响应面法(Box-Behnken)探索最佳制备工艺;将β-环糊精/薰衣草精油微胶囊掺入纺丝原液中,制备具有两级缓释作用的纳米纤维;利用热重分析仪、扫描电子显微镜、傅里叶变换红外光谱、水接触角对β-环糊精/薰衣草精油微胶囊及其纳米纤维的结构和性能进行表征。结果表明:β-环糊精1 g、薰衣草精油0.12 mL、包合温度39.2℃、搅拌时间1.48 h时,精油的包合率为83.2%,包合后精油的热稳定性提高;精油与β-环糊精之间没有形成新的化学键,21 d后微胶囊的芳香保持率为75.1%;微胶囊掺杂在纳米纤维中,纤维的疏水性能减弱,21 d芳香保持率为82.5%;微胶囊纳米纤维对薰衣草精油有很好的缓释作用,为芳香功能纺织品的设计提供了新思路。

In view of the high volatility and difficulty in lasting lavender essential oil of aromatherapy products in biological and pharmaceutical fields,β-cyclodextrin/lavender essential oil microcapsules were prepared by using lavender essential oil as the core material andβ-cyclodextrin as the wall material by saturated aqueous solution method using intermolecular complexation,and Box-Behnken method was used to explore the best preparation process.Microcapsules ofβ-cyclodextrin/lavender essential oil were mixed into spinning stock solution to prepare nanofibers with two-stage slow-release effect.The structures and properties ofβ-cyclodextrin/lavender essential oil microcapsules and their nanofibers were characterized by thermogravimetry,scanning electron microscopy,Fourier transform infrared spectroscopy and water contact angle.The results show that whenβ-cyclodextrin was 1 g,the essential oil dosage was 0.12 mL,the inclusion temperature was 39.2°C,and the stirring time was 1.48 h,the inclusion rate of the essential oil was 83.2%,and the thermal stability of the essential oil was improved after inclusion.No new chemical bonds were formed between the essential oil andβ-cyclodextrin,and the aroma retention rate of the microcapsules was 75.1%after 21 days.When microcapsules were doped in nanofibers,the hydrophobic properties of the fibers were weakened,and the aromatic retention rate was 82.5%after 21 days.Microencapsulated nanofibers have a good slow-release effect on lavender essential oil,which provides a new idea for the design of aromatic functional textiles.