摘要
Systemic light chain(AL)amyloidosis is a rare protein misfolding and deposition disorder.The clonal plasma cells in the bone marrow of AL amyloidosis patients secrete an abnormal immunoglobulin or its fragment,which is deposited in various organs and leads to organ dysfunction.The incidence in the USA is 8-14/million[1],whereas the incidence in China is undetermined.
作者
刘扬
Nelson Leung
路瑾
Yang Liu;Nelson Leung;Jin Lu(Peking University People’s Hospital,Peking University Institute of Hematology,National Clinical Research Center for Hematologic Disease,Beijing 100044,China;Division on Nephrology and Hypertension,Division of Hematology,Mayo Clinic,Rochester MN 55905,USA)