连云港市2012—2021年出生队列儿童EV 71型疫苗接种情况分析

Analysis of EV 71 vaccination status in Lianyungang City:a study from 2012-2021 birth cohort

目的分析连云港市2012—2021年出生队列儿童EV 71型疫苗接种现状,为制定疫苗接种策略和科学防控手足口病提供依据。方法利用江苏省预防接种综合服务管理信息系统建立自2017年EV 71型疫苗在连云港市开始接种以来适龄儿童的出生队列,分析出生队列儿童EV 71型疫苗接种情况。结果连云港市2012—2021年出生队列儿童500016名。截至2021年12月31日,连云港市2012—2021年出生队列儿童接种首剂EV 71型疫苗71715人,接种率为14.34%;完成全程接种60915人,全程接种率为12.18%。2012—2017年出生队列儿童EV 71型疫苗接种率和全程接种率在2018年度最高,2018—2020年出生队列儿童EV 71型疫苗接种率和全程接种率在出生后第2年最高。接种首剂EV 71型疫苗年龄中位数为14月龄(IQR为15月龄)。流动儿童、市区儿童、女童的EV 71型疫苗接种率及全程接种率均较高(均P<0.01)。结论连云港市2012—2021年出生队列儿童EV 71型疫苗接种率有所上升,但总体水平仍然较低。免疫起始月龄较晚,居住属性、居住地区、性别不同的儿童EV 71型疫苗接种情况存在一定差异,需针对性开展工作。

Objective To analyze the EV 71 vaccination status in the 2012-2021 birth cohort in Lianyungang City and provide a basis for formulating vaccination strategies and scientific prevention and control of hand-foot-mouth disease.Methods Using the Jiangsu Vaccination Provincial Management Information System,we established the birth cohort of age-eligible children since EV 71 vaccination began in 2017 in Lianyungang City,and analyzed the EV 71 vaccination status of these children.Results A total of 500016 children managed in the 2012-2021 birth cohort in Lianyungang City.As of December 31,2021,71715 children in the 2012-2021 birth cohort in Lianyungang City had received the first dose of EV 71 vaccine,with a vaccination rate of 14.34%;60915 children were whole-course vaccinated,with a whole-course vaccination rate of 12.18%.The vaccination rate and whole-course vaccination rate of EV 71 vaccine were highest in 2018 for children in the 2012-2021 birth cohort,and the highest in the second year of life for children in the 2018-2020 birth cohort.The median age for the first dose of vaccination was 14 months(interquartile range 15 months).Migrant children,urban children,and girls had higher EV 71 vaccination rate and whole-course vaccination rate(all P<0.01).Conclusions The EV 71 vaccination rate of children in the 2012-2021 birth cohort in Lianyungang City has increased but is still relatively low.Due to the late age of starting immunization,there are some differences in EV 71 vaccination among children with different residential attributes,residential regions,and gender,requiring targeted work.