峡部甲状腺乳头状癌颈部淋巴结转移风险因素及治疗的研究进展

Research Progress in Risk Factors and Treatment of Cervical Lymph Node Metastasis from Isthmus Papillary Thyroid Carcinoma

甲状腺乳头状癌(PTC)是甲状腺癌中最常见的病理类型,颈部淋巴结转移是其主要转移途径。由于甲状腺峡部特殊的解剖特点,位于峡部的PTC较位于腺叶的PTC具有更高的侵袭性。因此,峡部PTC(iPTC)颈部淋巴结转移的潜在风险因素及治疗方式值得关注。目前尚缺乏针对性的指南和专家共识指导iPTC的手术方式及颈部淋巴结清扫范围。分析iPTC颈部淋巴结转移风险因素(性别、年龄、肿瘤大小等)及不同手术范围选择的临床数据,可为iPTC的精准临床诊治提供新思路。

Papillary thyroid carcinoma(PTC)is the most common type of thyroid cancer,with metastasis to the lymph nodes in the neck being the main route of metastasis.Due to the special anatomical features of the isthmus,PTC located in the isthmus is more aggressive than PTC located in the lobe.Therefore the potential risk factors and treatment modalities of cervical lymph node metastasis of PTC in the isthmus(iPTC)deserve more attention.There is a lack of specific guidelines and expert consensus on the surgical approach and extent of cervical lymph node dissection for iPTC.The analysis on the clinical data of the risk factors of cervical lymph node metastasis of iPTC such as(age,gender,tumor size,etc.)and different surgical scope optionscan provide new ideas for precise clinical diagnosis and treatment of iPTC.