富血小板血浆在乳腺相关疾病中的应用进展

Progress in Application of Platelet-rich Plasma in Breast Related Diseases

乳腺疾病常困扰女性身心健康,手术治疗后面临脂肪重建坏死、存活率低及伴发血清肿等问题,目前尚缺乏有效治疗方案。部分乳腺炎和乳房慢性创伤伤口较难治愈,常规治疗效果不佳。富血小板血浆(PRP)富含多种活性因子,可通过促进脂肪移植颗粒存活和血管生成、增加组织间黏附、提供营养并发挥抗炎抗菌作用,进而减少血清肿形成,促进乳腺难愈伤口恢复,提高乳房重建、整形的成功率并创造抗炎环境提高乳腺炎治愈率。因此,深入研究PRP在乳腺相关疾病中的具体作用机制,可以为疾病的治疗提供新思路。

Breast diseases often trouble the physical and mental health of women.After surgical treatment,the women patients have to face problems of fat reconstruction necrosis,low survival rate and complications such as seroma,for which there is no effective treatment plan so far.Some mastitis and chronic trauma wounds of breast are difficult to cure,and the efficacy of conventional treatment is not good.Platelet-rich plasma(PRP)is rich in a variety of active factors,which can promote the survival of fat graft particles and angiogenesis,increase intertissue adhesion,provide nutrition and play an anti-inflammatory and antibacterial role,thereby reducing the formation of seroma,promoting the recovery of refractory breast wounds,improving the success rate of breast reconstruction and plastic surgery,and creating an anti-inflammatory environment to improve the cure rate of mastitis.Therefore,in-depth study of the specific mechanism of PRP in breast related diseases can provide new ideas for the treatment.