血常规相关参数在肺炎支原体感染患儿中的变化及临床价值

Changes and Clinical Value of Blood Routine Parameters in Children Infected with Mycoplasma Pneumoniae

目的探讨血常规相关参数在肺炎支原体感染患儿中的变化及临床价值。方法回顾性选取2021年1月~2022年10月我院收治的肺炎支原体感染患儿102例作为观察组,根据患儿的预后情况分为预后不佳组(30例)和预后良好组(72例);并选择同期健康体检的正常儿童52例作为对照组。给予观察组患儿基础治疗联合阿奇霉素治疗。比较观察组和对照组、观察组治疗前后、预后不佳组和预后良好组的血常规相关参数。结果观察组白细胞计数、中性粒细胞、血小板分布宽度、单核细胞比例高于对照组,观察组血小板计数、淋巴细胞比例低于对照组;治疗后观察组白细胞计数、中性粒细胞、血小板分布宽度、单核细胞比例均低于治疗前,治疗后观察组血小板计数、淋巴细胞比例均高于治疗前;预后良好组白细胞计数、中性粒细胞、血小板分布宽度、单核细胞比例低于预后不良组,预后良好组血小板计数、淋巴细胞比例高于预后不良组,差异有统计学意义(P<0.05)。结论通过血常规相关参数变化的检测可有效预测肺炎支原体感染的发生、病情进展,且与临床治疗效果和预后密切相关,临床可通过检测血常规相关参数来预测或评估临床疗效及预后情况,为临床诊治提供强有力的参考。

Objective To investigate the changes and clinical value of blood routine parameters in children with Mycoplasma pneumoniae infection.Methods 102 children with mycoplasma pneumoniae infection admitted to our hospital from January 2021 to October 2022 were retrospectively selected as the observation group,and were divided into the poor prognosis group(30 cases)and the good prognosis group(72 cases)according to the prognosis of the children.Fifty-two healthy children were selected as control group.The observation group was given basic treatment combined with azithromycin.Blood routine parameters were compared between the observation group and the control group,before and after treatment,and between the poor prognosis group and the good prognosis group.Results The white blood cell count,neutrophil,platelet distribution width and monocyte ratio in the observation group were higher than those in the control group,while the platelet count and lymphocyte ratio in the observation group were lower than those in the control group.After treatment,the white blood cell count,neutrophil,platelet distribution width and monocyte ratio in observation group were lower than before treatment,while the platelet count and lymphocyte ratio in observation group were higher than before treatment.The white blood cell count,neutrophil,platelet distribution width and monocyte ratio in the good prognosis group were lower than those in the poor prognosis group,while the platelet count and lymphocyte ratio in the good prognosis group were higher than those in the poor prognosis group,with statistical significance(P<0.05).Conclusion The occurrence and progression of mycoplasma pneumoniae infection can be effectively predicted by detecting changes in blood routine related parameters,which is closely related to clinical treatment effect and prognosis.Clinical efficacy and prognosis can be predicted or evaluated by detecting blood routine related parameters,providing a strong reference for clinical diagnosis and treatment.