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Loss-of-function of zebrafish cdt1 causes retarded body growth and underdeveloped gonads resembling human Meier-Gorlin syndrome

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摘要 The cell cycle consists of four distinct phases:GO/Gl,S(DNA synthesis),G2,and M(mitosis).The Gl to S transition is typified by an accumulation of 4',6-diamidino-2-phenylindole(DAPI)signal that indicates the rapid DNA synthesis initiated at special sites on DNA,generally called the Ori(origin of replication)(Alfa et al.,1989).
出处 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CSCD 2023年第11期1037-1046,共10页 浙江大学学报(英文版)B辑(生物医学与生物技术)
基金 supported by the National Natural Science Foundation of China (Nos.31830113 and 31771596).
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