琼海市自然人群幽门螺杆菌感染的流行病学调查

Survey on the current status and analysis of risk factors of Helicobacter pylori infection in Qionghai City of Hainan province

目的对琼海市自然人群进行幽门螺杆菌(H.pylori)感染的流行病学调查,为本地区H.pylori的防治提供参考。方法采用整体分层随机抽样的方法选取琼海市四个镇共535名居民进行问卷调查和尿素^(14)C呼气试验,计算人群感染率,并分析感染相关危险因素。结果琼海市人群总感染率为42.8%。家庭月收入(χ^(2)=5.063,P=0.027)、进食瓜果蔬菜(χ^(2)=8.268,P=0.004)、便后洗手习惯(χ^(2)=6.389,P=0.015)和运动习惯(χ^(2)=5.164,P=0.028)与H.pylori感染有相关性。二元logistic回归分析后,家庭月收入较低(β=0.427)、定期锻炼(β=0.484)和进食瓜果蔬菜(β=0.617)是影响H.pylori感染的独立相关因素。结论琼海市的H.pylori感染率较全国平均水平低。家庭月收入较低是影响H.pylori感染的独立危险因素,定期锻炼和进食瓜果蔬菜是H.pylori感染的独立保护因素。

Objective To investigate the current status of Helicobacter pylori(H.pylori)infection in the natural population of Qionghai City,to explore its associated risk factors,and to provide reference for the prevention and treatment of H.pylori in the region.Methods A total of 535 residents from four towns in Qionghai City were selected for questionnaire survey and urea^(14)C breath test using an overall stratified random sampling method to calculate the infection rate and analyze the risk factors associated with the infection.Results The overall infection rate of the population in Qionghai was 42.8%.Monthly household income(χ^(2)=5.063,P=0.027),consumption of fruits and vegetables(χ^(2)=8.268,P=0.004),hand washing habits after defecation(χ^(2)=6.389,P=0.015)and regular exercise(χ^(2)=5.164,P=0.028)were associated with H.pylori infection.After binary logistic regression analysis,lower monthly household income(β=0.427),regular exercise(β=0.484)and consumption of fruits and vegetables(β=0.617)were independently associated factors influencing H.pylori infection.Conclusion The prevalence of H.pylori infection in Qionghai was lower than the national average.H.pylori infection was associated with lower monthly household income being an independent risk factor,and regular exercise and consumption of fruits and vegetables being independent protective factors.