摘要
报道一例应用传统药物甲氨蝶呤、阿维A胶囊等药物治疗仍无法控制病情的顽固性SAPHO综合征患者,应用阿达木单抗维持治疗6周、依奇珠单抗维持治疗6周后病情仍无法控制,最终调整用药为JAK抑制剂托法替布治疗75天后皮疹完全消退,指趾甲近端见光滑新甲,胸锁关节无压痛。
We report a case of refractory SAPHO syndrome in which the disease could not be controlled by traditional drugs such as methotrexate and aveloxan capsules.After 6 weeks of maintenance treatment with adalimumab and echizumab,the disease remained uncontrolled.The rash completely disappeared,smooth new nail proximal to the toenail,no pressure pain in the sternoclavicular joint,after 75 days of treatment with the JAK inhibitor tofacitab.
作者
赛雯雯
王广进
SAI Wenwen;WANG Guangjin(Hospital for Skin Diseases,Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2024年第1期50-52,共3页
China Journal of Leprosy and Skin Diseases
基金
山东省皮肤性病学临床医学研究中心。
