儿童食管狭窄的药物治疗

Drug treatment for esophageal stenosis in children

儿童食管狭窄在临床并不少见,其可引起呕吐、呛咳、吞咽困难以及营养不良等症状,严重影响患儿的生长发育。儿童食管狭窄以良性疾病为主,主要由先天性畸形或者后天性食管损伤引起,手术是治疗此类疾病的主要手段,包括内镜下的扩张、切开、支架植入及外科手术等。除手术干预,药物应用在该疾病治疗中亦起到了重要作用。文章就儿童食管狭窄发生机制及药物治疗进行了总结和概述。

Esophageal stenosis is not uncommon in children,which may lead to clinical symptoms such as vomiting,cough,dysphagia and malnutrition;as a result,the growth and development of the children are seriously affected.Benign esophageal stenosis in children is mainly benign and is mainly caused by congenital malformation or acquired esophageal injury,surgical management is the mainstay of therapy for the disease,which includes endoscopic dilation,incision,stent implantation,and surgical procedures,etc.In addition to surgical intervention,the application of different drugs also plays an important role in the treatment of the disease.This article summarized the mechanism and drug treatment of esophageal stenosis in children.