分子医学 搏浪蓝海--兼谈基础医学学科发展及教育教学

Molecular medicine,surfing the deeper blue--with discussion about discipline and curriculum development in basic medical sciences

分子生物学的发展和技术进步为现代遗传学研究奠定了坚实基础。继分子病的概念提出后,人类在病因学和遗传特征与规律等方面对疾病的认知空前深入。在此基础上,分子医学学科体系的建立和研究路径的完善推动了当代医学研究的快速发展。在不断取得突破的同时,分子医学渐渐成为在基础医学领域具有多学科及跨学科兼容性特征的共识性主题。本文结合分子医学的发展历史和对相关文献的综合解析,对国内医学院校基础医学专业在现阶段的发展策略进行思考,归纳出若干关于学科建设和教育教学方略的启示和观点。此外,还针对分子医学在迎接人工智能技术的影响和挑战时所面临的问题进行了初步分析与探讨。

The establishment and rapid development of molecular biology paved the solid foundation for modern genetics and substantially reshaped related medical research.The human understanding of various diseases in aspect of etiology and genetic profiles has reached in-depth levels given the concept of molecular disease.As a novel discipline gradually established effective research strategy of principle features,including the theme of most consensus and accommodation for basic medical sciences,molecular medicine has made itself become a driving force to advance modern medicine.In this article,we introduced in brief the history of molecular medicine,explored retrospectively the literature contributed by molecular medicine focusing affiliations along medicine,and provided several consideration that might be helpful to the current discipline and curriculum development of basic medicine education,especially for domestic institution in medical universities.In addition,we also discussed in brief the adaptation to the impact or challenge from upcoming trend of artificial intelligence.