带量采购模式下某院质子泵抑制剂应用情况分析

Analysis on the Application of Proton Pump Inhibitors in A Hospital under the Mode of Volume-based Procurement

目的分析药品“4+7”带量采购对医院质子泵抑制剂(PPIs)应用的影响。方法选取该院THIS系统中“4+7”带量采购前(2019年4月24日~2020年4月23日)和带量采购后两年(2020年4月24日~2022年4月23日)质子泵抑制剂药品生产企业、价格、消耗量、使用频度、销售金额等数据,比较各类质子泵抑制剂的供应目录、销售价格、用药频度(DDDs)、销售金额、限定日费用(DDDc)、排序比(B/A)。结果带量采购政策执行两年后我院PPIs降价品规数达到12个,降价幅度在7.02%~92.25%之间。总DDDs呈逐年下降趋势,其中口服剂型的DDDs波动增长,同比带量采购前增幅5.21%,注射剂型的DDDs逐年下降,同比带量采购前最大降幅51.26%。总DDDc呈逐年下降趋势,最大降幅45.52%。PPIs原研品种使用占比持续下降,低于仿制品种。结论带量采购使PPIs使用结构发生变化,减轻患者用药负担。

OBJECTIVE To analyze the influence of“4+7”volume-based procurement on the application of proton pump inhibitors(PPIs)in hospitals.METHODS Select the data of PPI manufacturers,price,consumption,defined daily dosages and sales amount before the“4+7”volume-based procurement(April 24,2019-April 23,2020)and two years after the volume-based procurement(April 24,2020-April 23,2022)in THIS system of the hospital.The supply list,selling price,defined daily dosages(DDDs),selling sum,defined daily dose cost(DDDc)and ranking ratio(B/A)of various PPIs were compared.RESULTS After two years of implementation with volume-based procurement,the price reduction of PPIs in our hospital reached 12 typrs,and the price reduction range was 7.02%-92.25%.The total DDDs showed a downward trend year by year.Among them,DDDs of oral dosage forms fluctuated and increased by 5.21%compared with that before the volume-based procurement,while the DDDs of injectable dosage form decreased year by year with the largest decrease of 51.26%compared with that before volume-based procurement.The total DDDc showed a decreasing trend year by year,with a maximum decrease of 45.52%.The proportion of use of original PPIs decreased continuously,which was lower than that of generic varieties.CONCLUSION Volume-based procurement can change the use structure of PPIs and reduce the phamaceutical financial burden of patients.