彩色多普勒超声诊断卵巢癌周围血管侵袭的价值

Clinical value of color Doppler ultrasound in diagnosis of peripheral vascular invasion of ovarian cancer

目的分析彩色多普勒超声对卵巢癌周围血管侵袭的诊断价值。方法抽取2020年7月至2022年6月南阳市第一人民医院收治的卵巢癌患者89例,均行二维超声和彩色多普勒超声检查。以病理检查为"金标准",比较二维超声和彩色多普勒超声对卵巢癌周围血管侵袭的诊断结果及诊断效能,分析彩色多普勒超声对卵巢癌可切除状况的诊断结果,比较可切除和不可切除卵巢癌患者的彩色多普勒超声血流频谱参数[动脉血管舒张末期流速(EDV)、峰值流速(PSV)、阻力指数(RI)、搏动指数(PI)]。结果89例卵巢癌患者中,经病理检查确诊周围血管侵袭54例,周围血管未侵袭35例;二维超声诊断出周围血管侵袭50例,周围血管未侵袭39例;彩色多普勒超声诊断出周围血管侵袭55例,周围血管未侵袭34例。彩色多普勒超声诊断卵巢癌周围血管侵袭的敏感性、特异性、准确性分别为98.15%(53/54)、94.29%(33/35)、96.63%(86/89),高于二维超声的72.22%(39/54)、68.57%(24/35)、70.79%(63/89),P<0.05。89例卵巢癌患者中,经病理检查确定可切除33例,不可切除56例;经彩色多普勒超声诊出可切除32例,不可切除57例;彩色多普勒超声诊断卵巢癌可切除的敏感性、特异性、准确性分别为93.94%(31/33)、98.21%(55/56)、96.63%(86/89)。可切除卵巢癌患者的EDV、PSV水平低于不可切除患者,RI、PI水平高于不可切除患者(P<0.05)。结论彩色多普勒超声应用于卵巢癌周围血管侵袭诊断中,能提升诊断敏感性、特异性和准确性,可有效评估周围血管侵袭程度,判断肿瘤的可切除性。

ObjectiveTo analyze the clinical value of color Doppler ultrasound in the diagnosis of peripheral vascular invasion of ovarian cancer.MethodsA total of 89 patients with ovarian cancer treated in Nanyang First People’s Hospital from July 2020 to June 2022 were selected.All the patients underwent 2-dimentional ultrasound and color Doppler ultrasound examinations.Taking the pathological examination as the gold standard,the diagnostic results and efficacy of 2-dimentional ultrasound and color Doppler ultrasound in the diagnosis of peripheral vascular invasion of ovarian cancer were analyzed.And the diagnostic results of color Doppler ultrasound in the diagnosis of resectable status of ovarian cancer were statistically analyzed.The blood flow spectrum parameters of color Doppler ultrasound,including end-diastolic velocity(EDV),peak systolic velocity(PSV),resistance index(RI)and pulsation index(PI),of patients with resectable and unresectable ovarian cancer were compared.ResultsAccording to pathological examination,54 of 89 patients with ovarian cancer were diagnosed with peripheral vascular invasion,and 35 cases were diagnosed without peripheral vascular invasion.A total of 50 cases with peripheral vascular invasion and 39 cases without peripheral vascular invasion were identified by 2-dimentional ultrasound.A total of 55 cases with peripheral vascular invasion and 34 cases without peripheral vascular invasion were identified by color Doppler ultrasound.The diagnostic sensitivity,specificity and accuracy of color Doppler ultrasound in diagnosing peripheral vascular invasion of ovarian cancer were 98.15%(53/54),94.29%(33/35)and 96.63%(86/89),respectively,which were higher the 72.22%(39/54),68.57%(24/35)and 70.79%(63/89)of 2-dimentional ultrasound(P<0.05).Among the 89 patients with ovarian cancer,33 cases were resectable,and 56 cases were unresectable according to pathological examination;and 32 cases were confirmed as resectable,and 57 cases were confirmed as non resectable by color Doppler ultrasound;the sensitivity,specificity and accuracy of color Doppler ultrasound in the diagnosis of resectable ovarian cancer were 93.94%(31/33),98.21%(55/56)and 96.63%(86/89),respectively.The levels of EDV and PSV in patients with resectable ovarian cancer were lower than those in the patients with unresectable ovarian cancer,while RI and PI were higher than those in patients with unresectable ovarian cancer(P<0.05).ConclusionsThe application of color Doppler ultrasound in the diagnosis of peripheral vascular invasion of ovarian cancer can improve the diagnostic sensitivity,specificity and accuracy,effectively evaluate the degree of peripheral vascular invasion,and determine the resectability of the tumor.