Glubran-2胶经导管动脉栓塞治疗经皮肝穿刺胆道引流术后出血

Transcatheter arterial embolization with Glubran-2 glue for treating hemorrhage after percutaneous transhepatic cholangial drainage

目的观察以Glubran-2胶经导管动脉栓塞(TAE)治疗经皮肝穿刺胆道引流术(PTCD)后出血的效果。方法回顾性分析17例接受Glubran-2胶TAE治疗PTCD后出血的患者,观察技术成功率、临床成功率及并发症情况;比较TAE后当日与次日红细胞(RBC)及血红蛋白(Hb)差异;比较TAE前与TAE次日及第2日、TAE前与TAE后第4日谷丙转氨酶(GPT)差异。结果17例均经TAE成功栓塞责任血管,技术成功率及临床成功率均为100%;均未出现肝脓肿、败血症及肺栓塞等严重并发症。TAE后当日与次日,RBC及Hb差异均无统计学意义(P均>0.05);TAE前GPT低于TAE后次日及第2日(P<0.05),TAE前与TAE后第4日GPT差异无统计学意义(P>0.05)。结论以Glubran-2胶行TAE治疗PTCD后出血安全、有效。

Objective To observe the effect of transcatheter arterial embolization(TAE)with Glubran-2 glue for treating hemorrhage after percutaneous transhepatic cholangial drainage(PTCD).Methods Data of 17 patients with hemorrhage after PTCD who underwent TAE with Glubran-2 glue were retrospectively analyzed.The technical success rate,clinical success rate and complications were observed.The red blood cell(RBC)and hemoglobin(Hb)on the day of TAE and the next day of TAE were compared,also the glutamic-pyruvic transaminase(GPT)level before TAE,on the next day of TAE,on the second and the fourth day after TAE,respectively.Results The offending vessel of bleeding was successfully embolized in all 17 cases,both technical success rate of TAE and clinical success rate of hemostasis were 100%.There was no serious complication such as liver abscess,septicemia nor pulmonary embolism.No significant difference of RBC nor Hb was found between the day of TAE and the next day of TAE(both P>0.05).GPT before TAE was lower than the next day of TAE and the second day after TAE(P<0.05),while no significant difference of GPT was found before TAE and 4 days after TAE(P>0.05).Conclusion TAE with Glubran-2 glue for treating hemorrhage after PTCD was safe and effective.