PDSA循环在静脉用药调配残余量标准研究中的应用

Application of PDSA Circulation in the Study of Residue Standard of Intravenous Drug Formulation

目的利用PDSA循环方法制定静脉用药调配中心(PIVAS)注射用浓溶液调配残余量限度标准。方法参照PDSA循环过程,以我院PIVAS 2021年2月份5种不同标示装量注射用浓溶液调配后的安瓿瓶残骸残余量数据为循环前,5月份数据为循环后,根据文献制定初步标准限度并以达标率≥95%为质量改进目标,于3月至4月针对存在的问题制定改进措施并实施,分析PDSA循环前、后残余量平均值及残余量达标率,最终确定出适合我院PIVAS注射用浓溶液调配残余量的限度标准,6月至8月通过持续推进和抽检措施确定阶段改进成果。结果通过PDSA循环方法确定出适合我院PIVAS标示装量为1 mL、2 mL、5 mL、10 mL及20 mL注射用浓溶液调配残余量限度分别为<30μL、<60μL、<150μL、<200μL及<200μL。结论PDSA循环的运用可降低注射用浓溶液调配后残余量平均值,提高残余量达标率,在制定静脉用药调配残余量限度标准过程中可以将其作为质量控制工具应用。

OBJECTIVE Use the PDSA circulation method to establish the limit standard for the residual amount of injection concentrated solution formulation in the Intravenous Drug Administration(PIVAS).METHODS With reference to the PDSA circulation process,we collected the residual quantity data of ampoule remains after the preparation of five kinds of concentrated solutions for injection with different labeled volumes in our hospital.February 2021 was before the circulation,and the data in May was after the circulation.According to the literature,we formulated a preliminary standard limit and took the compliance rate≥95%as the quality improvement goal.From March to April,we formulated and implemented improvement measures against the existing problems,analyzed the average value of the residual quantity before and after the PDSA circulation and the compliance rate of the residual quantity,Finally,a limit standard suitable for the residual amount of concentrated solution for PIVAS injection in our hospital has been determined.From June to August,the stage improvement results will be determined through continuous promotion and sampling measures.RESULTS The PDSA circulation method was used to determine the residual limit suitable for the preparation of concentrated solution for PIVAS injection in our hospital,as follows:the limit standard is<30μL for 1 mL,<60μL for 2 mL,<150μL for 5 mL,<200μL for 10 mL,and<200μL for 20 mL.CONCLUSION The application of PDSA cycle can reduce the average residual amount after the preparation of concentrated solution for injection,improve the rate of residual amount reaching the standard,and can be used as a quality control tool in the process of formulating residual amount limit standards for intravenous drug formulation.