肝多房棘球蚴病导致肝硬化的研究进展

Research progress in hepaticalveolar echinococcosis leading to cirrhosis

多房棘球蚴病是一种由多房棘球绦虫感染而引起的人兽共患寄生虫病。肝脏是多房棘球蚴病的原发器官,病灶呈浸润性生长,故有“虫癌”之称。根治性病灶切除术是治疗肝多房棘球蚴病的首选且有效方法。终末期肝多房棘球蚴病多合并有寄生虫性肝硬化,如继发性胆汁性肝硬化、淤血性肝硬化或布加综合征。目前,关于肝多房棘球蚴病导致肝硬化的研究较少,本文就肝多房棘球蚴病灶侵犯肝内重要血管、胆管而导致继发性胆汁性肝硬化或淤血性肝硬化等方面作一综述。

Alveolar echinococcosis is a zoonotic parasitic disease caused by an infection with Echinococcosis multilocularis.The liver is the primary organ of alveolar echinococcosis.Alveolar echinococcosis is usually characterized by invasive growth and consequently iscalled“parasitic cancer.”Resection of radical lesions is a preferred and effective treatment for hepatic alveolar echinococcosis.End-stage hepatic alveolar echinococcosis often occurs with parasiticcirrhosis,such as secondary biliary cirrhosis,congestive liver cirrhosis or Budd-Chiari syndrome.Few studies have examined hepatic multilocular echinococcosis leading to cirrhosis.This article reviews the aspects of hepatic alveolar echinococcosis involving the invasion of important blood vessels and bile ducts,thereby leading to secondary biliary cirrhosis and congestive liver cirrhosis caused by hepatic alveolar echinococcosis.