肺保护性通气策略在妇科腹腔镜手术中的研究进展

Research Progress of Lung Protective Ventilation Strategy in Gynecological Laparoscopic Surgery

全麻术中机械通气相关性肺损伤可导致肺功能下降,是影响患者预后及康复的关键因素之一。妇科腹腔镜手术要求的头低脚高体位(Trendelenburg体位)、术中二氧化碳气腹,可对患者的生理功能产生严重的干扰,使麻醉期间的呼吸管理变得更加复杂。围术期采取肺保护性通气策略,可改善围术期氧合功能,抑制氧化应激及炎症反应,从而预防和减少术后肺部并发症的发生,缩短住院时间。近年来随着快速康复外科的不断进步,围术期进行肺保护性通气策略对于预防、治疗机械通气相关性肺损伤,具有越来越重要的意义。

Lung injury related to mechanical ventilation during general anesthesia leads to decreased lung function,which is one of the key factors affecting the prognosis and rehabilitation of patients.The Trendelenburg position and intraoperative carbon dioxide pneumoperitoneum,required for gynecological laparoscopic surgery,can cause serious interference in the patient's physiological functions,making respiratory management during anesthesia more complicated.Perioperative lung protective ventilation strategy can improve perioperative oxygenation function,inhibit oxidative stress and inflammatory reaction,thus preventing and reducing postoperative pulmonary complications and shortening hospital stay.With the continuous progress of the rehabilitation surgery,Perioperative lung protection ventilation strategy has become more and more important for the prevention and treatment of mechanical ventilation-related lung injury.