摘要
β-酮砜是一类重要的含硫化合物和有机合成中间体,被广泛应用于天然产物及许多重要有机化合物的构筑.开发了一种溴化铜催化烯醇硅醚与芳基亚磺酸钠快速合成β-酮砜的方法,具有操作简单、条件温和和反应时间短等优点.
β-Keto sulfones are an important group of sulfur-containing compounds and intermediates for organic synthesis,which are widely used in the construction of natural products and various important organic compounds.A method for the rapid synthesis ofβ-keto sulfones catalyzed by copper bromide from enol silyl ether and sodium arylsulfinates is developed,which has the advantages of simple operation,mild conditions and short reaction time.
作者
许力
吕兰兰
王香善
Xu Li;LüLanlan;Wang Xiangshan(School of Chemistry and Materials Science,Jiangsu Normal University,Xuzhou,Jiangsu 221116)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2023年第10期3644-3651,共8页
Chinese Journal of Organic Chemistry
基金
江苏省高校面上项目(No.22KJD150003)
2023年度江苏师范大学实验室研究课题(No.L2023YB08)资助项目。
关键词
β-酮砜
铜催化
烯醇硅醚
芳基亚磺酸钠
β-keto sulfone
copper catalysis
enol silyl ether
sodium arylsulfinate
