湖南省首例儿童X群流行性脑脊髓膜炎病例报告及文献复习

First case of group X meningococcal disease in Hunan Province:case report and literature review

X群流行性脑脊髓膜炎在国内和发达国家罕见,湖南省尚未发现相关病例报道。X群流行性脑脊髓膜炎患者,临床易出现病情进展迅速及危重情况,不积极治疗易遗留严重并发症。目前没有获得许可的脑膜炎奈瑟菌X群疫苗。本文收集湖南省首例X群重症流行性脑脊髓膜炎患者的症状、体征、辅助检查和治疗经过等资料,并结合相关文献进行复习,旨在提高临床医生对X群流行性脑脊髓膜炎的认识,早期识别、诊治该病。

The group X meningococcal disease is rare in China and developed countries.No related cases have been reported in Human Province.The disease progresses rapidly and leads to critical severity.Serious complications may occur,if not treated actively.Group X Neisseria meningitidis(Nm X)vaccine has not yet obtained permission at present.This paper collects data on the symptoms,signs,auxiliary examinations,and treatment process of the first patient with severe group X meningococcal disease in Hunan Province,reviews relevant literatures,so as to improve clinicians’understanding on group X meningococcal disease,conduct early identification,diagnosis and treatment of the disease.