基于数据挖掘探讨黄斌教授治疗高血压用药规律

Discussion on Professor Huang Bin’s medication law in treating hypertension based on data mining

目的基于中医传承计算平台(V3.0)探究黄斌教授治疗高血压的用药规律。方法收集黄斌教授在河南省中医院(河南中医药大学第二附属医院)于2019年6月至2022年12月门诊诊治高血压患者的病历,借助中医传承计算平台(V3.0)对收集的病历进行统计分析,探寻黄斌教授在高血压辨治中的处方特点、用药规律。结果共涉及处方340首,中药196味,使用总频次达4995次,使用频次>100次的药物有14味;药物四气以寒、平、温为主,五味以甘、苦、辛为主,主要归肝、脾经;关联分析得出到14组药物核心组合,13对高关联核心药对;聚类分析得出4个核心组方。结论黄教授治疗高血压以治疗实证为主,多从痰湿论治,兼顾调畅情志。

Objective To explore the medication rule of Professor Huang Bin in the treatment of hypertension based on traditional Chinese medicine inheritance computing platform(V3.0).Methods The medical records of hypertensive patients treated by Professor Huang Bin in the Department of Outpatient of Henan Hospital of Traditional Chinese Medicine(the Second Affiliated Hospital of Henan University of Chinese Medicine)from June 2019 to December 2022 were collected.The collected medical records were statistically analyzed with the traditional Chinese medicine inheritance computing platform(V3.0),and the prescription characteristics and medication rules of Professor Huang Bin in the treatment of hypertension were explored.Results A total of 340 prescriptions were involved,196 kinds of traditional Chinese medicine,and the total frequency of use was 4995 times,and 14 kinds of drugs were used more than 100 times.The four nature of drugs were mainly cold,plain,and warm,and the five flavours were mainly sweet,bitter,and pungent,which mainly return to the liver and spleen channels.Association analysis showed that there were 14 groups of drug core combinations and 13 pairs of high association core couplet medicines.Four core formulas were obtained by cluster analysis.Conclusion Professor Huang’s treatment of hypertension is mainly based on excess syndrome treatment,mostly from phlegm-dampness treatment,taking into account the regulation of emotions.