通窍鼻炎颗粒在风热犯肺证变应性鼻炎患者中的临床应用

Clinical application of Tongqiao Biyan Granules in allergic rhinitis patients with syndrome of wind-heat invading lung

目的观察通窍鼻炎颗粒在风热犯肺证变应性鼻炎患者中的临床应用。方法选取2019年8月至2022年8月就诊于江苏省苏州市立医院北区的风热犯肺证变应性鼻炎患者102例,以随机数字表法将其分为联合组(51例)、常规组(51例)。常规组接受左西替利嗪治疗,联合组使用左西替利嗪联合通窍鼻炎颗粒。两组均持续治疗3周。比较两组临床疗效及治疗前后的症候评分、体征评分、嗅觉识别阈值,记录两组不良反应发生情况。结果联合组临床疗效优于常规组,差异有统计学意义(P<0.05)。治疗后,两组症候、体征评分及嗅觉识别阈值均低于治疗前,且联合组低于常规组,差异有统计学意义(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论通窍鼻炎颗粒联合左西替利嗪可改善风热犯肺证变应性鼻炎患者临床症状,疗效确切,可降低患者嗅觉识别阈值,且安全,值得推广。

Objective To observe the clinical application of Tongqiao Biyan Granules in allergic rhinitis patients with syndrome of wind-heat invading lung.Methods A total of 102 allergic rhinitis patients with syndrome of wind-heat invading lung admitted to the North District,Suzhou Municipal Hospital,Jiangsu Province from August 2019 to August 2022 were selected and divided into combined group(51 cases)and routine group(51 cases)by random number table method.The routine group was treated with Levocetirizine,and the combined group was treated with Levocetirizine combined with Tongqiao Biyan Granules.Both groups were treated for three weeks.The clinical efficacy,and symptom score,sign score,olfactory recognition threshold before and after treatment were compared between the two groups,and the occurrence of adverse reactions were recorded.Results The clinical effect of the combined group was better than that of the routine group,and the difference was statistically significant(P<0.05).After treatment,the symptoms,signs scores,and olfactory recognition threshold of the two groups were lower than those before treatment,and those of combined group were lower than those of control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Tongqiao Biyan Granules combined with Levocetirizine can improve the clinical symptoms of allergic rhinitis patients with syndrome of wind-heat invading lung,and can reduce the olfaction recognition threshold of patients,and is safe,worthy of promotion.