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系统性免疫炎症指数在临床应用中的研究进展

Progress in clinical application of systemic immune-inflammatory index
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摘要 系统性免疫炎症指数(SII)是评估免疫系统功能的一种新的评分系统,定义为血小板数×中性粒细胞数/淋巴细胞计数的比值,其将血小板、中性粒细胞及淋巴细胞结合在一起,可以更好地评估患者的免疫及炎症状况。近年来许多研究表明,SII越来越多地用于肿瘤、心脑血管疾病、炎症相关疾病预后的评价指标,其在许多疾病的应用价值优于中性粒细胞淋巴细胞比值(NLR)、血小板淋巴细胞比值(PLR)等传统指标,且其计算简单、检测指标成本低、重复性好,在临床推广容易,已经受到广大临床工作者的关注。该文就近年对SII在临床中的应用进展进行综述,让广大临床工作者更全面地了解SII,以期更好地在临床中应用,最终使患者从中受益。 The systemic immune-inflammatory index(SII)is a new scoring system for evaluating immune system function.It is defined as the ratio of platelet count x neutrophil count/lymphocyte count.It combines platelets,neutrophils,and lymphocytes to better evaluate the immune and inflammatory status of patients.In recent years,many studies have shown that the SII is increasingly used to evaluate the prognosis of tumors,cardiovascular and cerebrovascular diseases,and inflammation-related diseases,and its application value in many diseases is better than the traditional indicators such as neutrophil-lymphocyte ratio(NLR)and platelet-lymphocyte ratio(PLR).Moreover,it has simple calculation,low cost of detection index,good repeatability,easy to promote in clinical practice,and has attracted the attention of clinical workers.This article reviews the recent progress in the clinical application of SII,so that the majority of clinical workers have a more comprehensive understanding of SII,in order to better clinical application,and ultimately benefit patients.
作者 陈宏涛 肖东 郭仁楠 CHEN Hongtao;XIAO Dong;GUO Rennan(Graduate School of Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumqi830011,China;Department of Intensive Care Medicine,Xinjiang Uygur Autonomous Region People's Hospital,Xinjiang Uygur Autonomous Region,Urumqi830054,China)
出处 《中国当代医药》 CAS 2023年第35期25-30,共6页 China Modern Medicine
基金 新疆维吾尔自治区科技计划项目(2021D01C155)。
关键词 系统性免疫炎症指数 临床应用 预后 研究进展 Systemic immune-inflammatory index Clinical application Prognosis Research progress
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