产前超声筛查胎儿脑室增宽在评估不良妊娠结局中的应用

Application of prenatal ultrasound screening for fetal ventricle widening in the assessment of adverse pregnancy outcomes

目的产前超声筛查胎儿脑室增宽在评估不良妊娠结局中的应用价值。方法回顾性分析2016年1月至2021年1月福建省妇幼保健院超声诊断83例胎儿脑室增宽妊娠病例的临床资料。分析产前超声对胎儿脑室增宽和非孤立性脑室增宽的检出率,比较孤立性脑室增宽和非孤立性脑室增宽对评估不良妊娠结局的意义。结果产前胎儿及产后新生儿头颅彩超检测不同程度脑室增宽检出情况比较,差异无统计学意义(P>0.05)。产前胎儿检出非孤立性脑室增宽共42例(50.60%),产后随访新生儿头颅彩超检出非孤立性脑室增宽共41例(49.40%),其中神经系统异常(29 vs.28)例、心血管系统异常(5 vs.5)例、骨骼系统异常(4 vs.4)例、胎盘异常(4 vs.4)例,差异无统计学意义(P>0.05)。孤立性脑室增宽胎儿的不良妊娠结局发生率为21.95%(9/41),低于非孤立性脑室增宽胎儿的45.24%(19/42),差异有统计学意义(P<0.05)。结论产前彩色多普勒超声对胎儿脑室增宽的诊断准确率高,其中检测出非孤立性脑室增宽胎儿发生不良妊娠结局的风险较高,需临床重点关注。

Objective To study the application value of prenatal ultrasound screening for fetal ventricle widening in the assessment of adverse pregnancy outcomes.Methods A total of 83 cases of fetal ventricle widening pregnancy diagnosed by ultrasound from January 2016 to January 2021 in Fujian Maternity and Child Health Hospital were retrospectively analyzed.The detection rate of fetal ventricle widening and non-isolated ventricle widening were analyzed by prenatal ultrasound,and the significance of isolated ventricle widening and non-isolated ventricle widening in evaluating adverse pregnancy outcomes were compared.Results There were no significant differences in prenatal fetal and postpartum neonatal head color ultrasound detection of different degrees of ventricular widening(P>0.05).A total of 42(50.60%)cases of non-isolated ventricular widening were detected in prenatal fetuses,and 41 cases(49.40%)were detected in postpartum neonatal head color ultrasound.There were no significant differences in nervous system abnormalities(29 vs.28),cardiovascular system abnormalities(5 vs.5),skeletal system abnormalities(4 vs.4)and placenta abnormalities(4 vs.4)(P>0.05).The incidence of adverse pregnancy outcome of isolated ventricular widening was 21.95%(9/41),which was significantly lower than that of non-isolated ventricular widening 45.24%(19/42),and the difference was statistically significant(P<0.05).Conclusion Prenatal color Doppler ultrasound has a high diagnostic accuracy for fetal ventricular widening,and fetuses with non-isolated ventricular widening detected have a higher risk of adverse pregnancy outcomes,which needs clinical attention.