高原环境对腹部创伤部位细菌性感染的影响及特点综述

Effect and characteristic analysis of high altitude environment on bacterial infection of abdominal wound sites

高原特殊环境具有低大气压、低氧分压和气候寒冷干燥等多种特点,在此环境下发生的创伤特点异于平原环境。本文综述了高原特殊环境对腹部创伤部位感染的影响及特点,并分析了可能机制。高原低温环境下细菌生长繁殖缓慢,创伤部位污染菌量到达感染临界值的时间显著延长,创伤部位感染相对静止期延长。但长期处于低氧分压和低温环境,会造成创伤部位愈合延迟,加之高原环境对机体各项功能的影响,可能会造成创伤部位易发生细菌感染且增强感染的严重性。相比平原环境,高原特殊环境下腹部创伤部位感染的细菌谱也有变化,但各项高原研究间的结果存在较大差异。

The characteristics of trauma in high altitude environment with low atmospheric pressure,low oxygen partial pressure,cold and dry climate are different from those in plain environment.This paper reviews the effects and characteristics of high altitude environment on abdominal wound site infection,and analyzes its possible mechanism.Bacterial growth and reproduction are slow in low temperature environment in the plateau,the time for the count of contaminated bacteria at the wound site to the critical value of infection is significantly prolonged as well as the relative quiescent period of the wound site infection.However,healing of the wound site would be delayed due to long-term exposure to low oxygen partial pressure and low temperature and other characteristics of the environment,and the wound site would be more prone to severe bacterial infection coupled with the impact of the plateau environment on various body functions.Therefore,the specific influence and mechanism of different altitude plateau environment on bacterial infection of abdominal wound site needs to be further clarified and studied.