立构复合调控聚乳酸基材料性能及其应用研究进展

Research Progress on the Properties and Applications of Poly(Lactide)-Based Materials Adjusted by Stereocomplexation

从外场环境、异相成核剂和分子结构等三个方面综述了影响左旋聚乳酸(PLLA)和右旋聚乳酸(PDLA)间立构复合的主要因素,并对立构复合调控聚乳酸基材料性能的主要途径(立构复合成核剂、立构复合交联点及其立构复合网络、立构复合界面、完全立构复合/高立构复合程度)进行了总结。综述了立构复合聚乳酸基材料在药物载体、组织工程、包装、环境、功能材料和其他等领域的应用,对其未来的发展方向进行了展望。

The main factors affecting the stereocomplexation between poly(L-lactide)(PLLA)and poly(D-lactide)(PDLA)were reviewed from external field environment,heterogeneous nucleators and molecular structure.The ways of adjusting the properties of poly(lactide)-based materials by stereocomplexation were summarized,including stereocomplex nucleating agent,stereocomplex-crosslinking point and its stereocomplex network,stereocomplex interface,full stereocomplexation/high stereocomplexation degree.Further,the applications of stereocomplexation poly(lactide)-based materials in drug carriers,tissue engineering,packaging,environment,functional materials and other fields were reviewed,and the future development direction was also prospected.