伴有丙型病毒性肝炎的精神分裂症患者的临床诊疗分析

Clinical diagnosis and treatment of schizophrenia patients with viral hepatitis C

抗精神病药物在治疗精神分裂症的过程中对血液系统会有一定影响,最多见的是白细胞和血小板的减少。丙型肝炎易发展为肝硬化,出现脾功能亢进,进而导致血细胞的减少。合并有丙型肝炎的精神分裂症患者服用抗精神病药物,会增加血细胞减少的风险,故在合并有肝病的精神分裂症患者在抗精神病药物选择中应遵循特殊用药原则,制定出个体化的药物治疗方案,慎用经肝脏代谢及对血液系统有影响的抗精神病药物。

Antipsychotic drugs will have certain influence on the blood system in the process of treating schizophrenia,the most common is the decrease of white blood cells and platelets.Hepatitis C is easy to develop into cirrhosis,with hypersplenism,which leads to the decrease of blood cells.Taking antipsychotic drugs in schizophrenic patients with hepatitis C will increase the risk of cytopenia.Therefore,in the selection of antipsychotic drugs in schizophrenic patients with liver disease,we should follow the principle of special medication,formulate an individualized drug treatment plan,and carefully use antipsychotic drugs that are metabolized by the liver and have an impact on the blood system.