基于功能核磁共振的中老年人吞咽任务脑功能区成像研究

Sltudy on Brain Functional Area Imaging of Swallowing Task of Middle-Aged and Elderly People Based on Functional Magnetic Resonance Imaging

目的探讨健康中老年人在执行吞咽任务时全脑激活区域的分布及特点。方法对10例右利手的健康中年老人执行吞咽任务,利用功能核磁共振成像技术观察受试者全脑激活的分布情况,采用SPM 12软件对功能成像数据进行处理及图像显示。结果执行吞咽任务时,多个脑区被激活,其中双侧中央前回、补充运动区、中央后回、基底神经节、岛叶、丘脑为主要激活的区域,左侧半球激活脑区多于右侧半球。结论初级感觉运动区、补充运动区、岛叶、丘脑等脑区是吞咽神经控制网络的一部分。

Objective To explore the distribution and characteristics of whole brain activation regions in healthy middle-aged and elderly people during swallowing tasks.Methods The swallowing task was performed on 10 healthy middle-aged and elderly people with right handedness.The distribution of brain activation was observed by functional magnetic resonance imaging.SPM 12 sofware was used to process and display the functional imaging data.Results When performing swallowing task,multiple brain regions were activated,of which bilateral precentral gyrus,supplementary motor area,postcentral gyrus,basal ganglia,insula and thalamus were the main activated regions,and more brain regions were activated in the left hemisphere than in the right hemisphere.Conclusions The brain regions of primary sensorimotor area,supplementary motor area,insula and thalamus are part of the swallowing neural control network.