认知训练联合行为干预对早中期原发性帕金森病患者焦虑、抑郁的影响

Effects of Cognitive Training Combined with Behavioral Intervention on Anxiety and Depression in Patients with Early and Middle Stage of Primary Parkinson Disease

目的:探讨认知训练联合行为干预对早中期原发性帕金森病患者焦虑抑郁的影响。方法:选取2020年12月—2022年1月滨州医学院附属医院神经内科收治的124例Hoehn-Yahr分级(HY)为早中期的原发性帕金森病患者,按照随机数字表法将研究对象分为对照组和观察组,各62例。对照组给予常规干预及护理,观察组在对照组基础上给予认知训练和行为干预。对比两组汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、蒙特利尔认知评估量表(MoCA)评分。结果:干预后6个月,观察组HAMA评分(17.18±3.80)分低于对照组(22.94±3.51)分,差异有统计学意义(P<0.05);观察组HAMD评分(17.37±3.78)分低于对照组(21.84±4.70)分,差异有统计学意义(P<0.05);观察组MoCA评分(25.97±2.13)分高于对照组(19.18±4.07)分,差异有统计学意义(P<0.05)。结论:认知训练联合行为干预能够改善早中期原发性帕金森患者焦虑、抑郁情绪。

Objective:To explore the effect of cognitive training combined with behavioral intervention on anxiety and depression in patients with early and middle stage of primary Parkinson disease.Method:A total of 124 patients with early and middle stage of primary Parkinson disease with Hoehn-Yahr classification(HY)admitted to the Department of Neurology,Binzhou Medical University Hospital from December 2020 to January 2022 were selected,and the subjects were divided into control group and observation group according to random number table method,with 62 cases each group.The control group was given routine intervention and nursing,and the observation group was given cognitive training and behavioral intervention on the basis of the control group.Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD)and Montreal cognitive assessment scale(MoCA)scores were compared.Result:Six months after intervention,HAMA score of the observation group(17.18±3.80)scores was lower than that of the control group(22.94±3.51)scores,the difference was statistically significant(P<0.05);HAMD score of the observation group(17.37±3.78)scores was lower than that of the control group(21.84±4.70)scores,the difference was statistically significant(P<0.05);the MoCA score of observation group(25.97±2.13)scores was higher than that of the control group(19.18±4.07)scores,the difference was statistically significant(P<0.05).Conclusion:Cognitive training combined with behavioral intervention can improve anxiety and depression mood in patients with primary Parkinson disease in the early and middle stages.