脓毒症相关性谵妄的研究进展

Research Progress of Sepsis-associated Delirium

谵妄的特征是急性精神状态改变,并伴有认知功能和注意力下降。脓毒症患者的谵妄,被称为脓毒症相关性谵妄(sepsis-associated delirium,SAD),它与在重症监护病房通常遇到的其他类型的谵妄有所不同。由于脓毒症和谵妄都与发病率和死亡率的增加密切相关,而且谵妄被认为是影响重症监护后综合征预后的重要因素,因此预防、及时诊断和治疗SAD至关重要。本文就包括新型冠状病毒感染在内的SAD的病因、发病机制、危险因素、分型、预防、诊断、治疗和预后进行综述和讨论。

Delirium is characterized by acute altered mental status and accompanied with decreased cognitive function and attention.Delirium in patients with sepsis,known as sepsis-associated delirium(SAD),is different from other types of delirium commonly encountered in intensive care units.Sepsis and delirium are strongly associated with increased morbidity and mortality,and delirium is considered an important factor affecting the prognosis of the post-intensive care syndrome,so it is very important of prevention,timely diagnosis,and treatment of SAD.This article reviews and discusses the etiology,pathogenesis,risk factors,typing,prevention,diagnosis,treatment and prognosis of SAD that including the COVID-19.