趋化因子受体对脑卒中的作用的研究进展

Research progress on role of chemokine receptors in stroke

脑卒中主要由脑血管破裂或局部血栓栓塞引起。脑卒中会导致免疫细胞大量浸润和神经胶质细胞活化等一系列炎症反应。趋化因子受体在机体炎症反应中发挥着不可或缺的作用,其调节机体免疫细胞的募集,参与机体的免疫反应。本文就趋化因子受体对脑卒中的作用的研究进展作一综述。

Stroke is mainly caused by cerebral vascular rupture or local thromboembolism.Stroke can lead to a series of inflammatory responses such as massive infiltration of immune cells and activation of glial cells.Chemokine receptors play an indispensable role in inflammatory response,regulating recruitment of immune cells and participating in immune response in body.The present article makes a review on research progress on role of chemokine receptors in stroke.