Antibiotics management in severe acute pancreatitis

Severe acute pancreatitis(SAP)is a common and critical disease.It is life-threatening at any time if multiple organ dysfunction occurs.SAP may develop secondary infection,often iatrogenic[1].To treat infected SAP,appropriate antibiotic use and nosocomial management is critical,along with adequate drainage of the infected foci and optimizing the immune function.Not only is the use of powerful antibiotics necessary to minimize mortality,but early use is also necessary to reduce the occurrence of drug-resistant bacteria.Therefore,antibiotic management is clinically important and requires careful attention.