服用二甲双胍的2型糖尿病患者进行碘造影剂检查的研究进展

Research progress of iodine contrast agent examination in patients with type 2 diabetes mellitus taking metformin

二甲双胍与碘造影剂近年来广泛应用于临床,由于二者同时使用存在造影剂诱导的急性肾损伤的风险,2型糖尿病(T2DM)患者往往被禁止或推迟使用碘造影剂的检查和治疗,导致误诊或延误治疗,对患者造成了间接伤害。因此,碘造影剂在T2DM患者中如何安全、规范使用一直是临床上关注的重点。本文通过分析整理二甲双胍和碘造影剂合用的临床研究和相关指南共识,探讨二者联合使用的安全性,以期为临床医生提供参考。

At present,metformin and iodine contrast agent are widely used in clinic.Due to the risk of acute renal injury induced by contrast medium,patients with type 2 diabetes mellitus(T2DM)are often prohibited or postponed the examination and treatment by iodine contrast agent,resulting in misdiagnosis or delay of treatment and indirect damage to patients.Therefore,how to safely and standardizedly use iodine contrast medium in patients with T2DM has been the focus of clinical attention.By analyzing the clinical research and related guidelines of metformin and iodine contrast agent,this paper discusses the safety of metformin and iodine contrast agent,in order to provide references for clinicians.