长期住院精神分裂症患者代谢综合征现状和相关影响因素

Current Status of Metabolic Syndrome and Related Influencing Factors in Long-term Hospitalized Schizophrenic Patients

目的探究长期住院精神分裂症患者伴发代谢综合征的现状和相关影响因素。方法方便选取2022年6—9月于天津市安定医院精神八科长期住院的98例精神分裂症患者作为研究对象,根据患者是否合并代谢综合征,将患者分为病例组和对照组,其中病例组39例,对照组59例,比较患者的各项临床资料及相关影响因素。结果对照组年龄小于65岁、单一用药的患者占比高于病例组,差异有统计学意义(P<0.05)。Logistic回归分析显示,性别、年龄、用药情况均为长期住院精神分裂患者伴发代谢综合征的风险因素(OR=3.262、2.344、3.381,P<0.05)。结论女性、年龄越大以及联合用药者更易合并代谢综合征,为临床早识别早发现以及降低精神分裂症患者伴发代谢综合征提供依据。

Objective To investigate the current status and related influencing factors of metabolic syndrome accompanying long-term hospitalized schizophrenic patients.Methods 98 patients with schizophrenia who were hospitalized for a long time in the eighth Department of Psychiatry,Tianjin Anding Hospital from June to September 2022 were conveniently selected as the study objects.According to whether the patients were complicated with metabolic syndrome,the patients were divided into case group and control group,including 39 cases in case group and 59 cases in control group.The clinical data and related influencing factors of the patients were compared.Results The proportion of patients younger than 65 years old in control group was higher than that in case group,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that gender,age and drug use were all risk factors for metabolic syndrome in patients with long-term hospitalized schizophrenia(OR=3.262,2.344,3.381,P<0.05).Conclusion Women,older age,and co-medication are more likely to be associated with metabolic syndrome,which provides a basis for early clinical identification and detection as well as reduction of associated metabolic syndrome in schizophrenic patients.